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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCN1L1
All Species:
4.55
Human Site:
S337
Identified Species:
12.5
UniProt:
Q92616
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92616
NP_006827.1
2671
292744
S337
S
D
S
S
A
M
E
S
L
T
K
H
L
F
A
Chimpanzee
Pan troglodytes
XP_001159608
2671
292720
S337
S
D
S
S
A
M
E
S
L
T
K
H
L
F
A
Rhesus Macaque
Macaca mulatta
XP_001087027
2601
285392
V311
V
S
G
P
S
S
Q
V
L
N
G
I
V
A
E
Dog
Lupus familis
XP_534701
2671
292720
A337
S
D
S
S
A
T
E
A
L
T
R
H
L
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510404
1592
172883
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663103
2281
249882
L208
L
G
Q
V
S
D
T
L
K
R
F
A
V
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392968
2646
293858
N335
S
D
T
I
A
L
E
N
L
L
S
S
V
F
A
Nematode Worm
Caenorhab. elegans
NP_497506
2680
294946
K344
S
E
I
S
V
I
Q
K
I
L
N
T
L
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33892
2672
296680
A316
S
I
L
S
E
L
Y
A
G
V
S
P
E
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.7
96.7
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
58.4
N.A.
N.A.
50.2
33
N.A.
Protein Similarity:
100
99.7
95.7
98.3
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
N.A.
66.8
N.A.
N.A.
68.4
54.4
N.A.
P-Site Identity:
100
100
6.6
80
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
46.6
20
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
73.3
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
45
0
0
23
0
0
0
12
0
12
45
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
0
0
0
12
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
12
0
0
12
0
45
0
0
0
0
0
12
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
45
0
% F
% Gly:
0
12
12
0
0
0
0
0
12
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% H
% Ile:
0
12
12
12
0
12
0
0
12
0
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
12
0
23
0
0
23
0
% K
% Leu:
12
0
12
0
0
23
0
12
56
23
0
0
45
12
0
% L
% Met:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
12
12
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
12
0
0
0
23
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% R
% Ser:
67
12
34
56
23
12
0
23
0
0
23
12
0
0
0
% S
% Thr:
0
0
12
0
0
12
12
0
0
34
0
12
0
0
0
% T
% Val:
12
0
0
12
12
0
0
12
0
12
0
0
34
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _